Synthesis of novel naphtho [2, 1-b] furo [3, 2-b] pyridine derivatives as potential antimicrobial agents

D Ramesh, C Chandrashekhar…

Index: Ramesh; Chandrashekhar; Vaidya Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 5 p. 753 - 758

Full Text: HTML

Citation Number: 15

Abstract

Abstract: The starting materials 2-acyl-3-aminonaphtho [2, 1-b] furans 4a-b have been directly synthesized from 2-hydroxy-1-naphthaldehyde oxime by treating with α-haloketone through Thrope-Ziegler reaction. The compounds 4a-b undergo Friedlander cyclization on ...