Enantioselective synthesis of vicinal halohydrins via dynamic kinetic resolution
A Ros, A Magriz, H Dietrich, R Fernández…
Index: Bowers, Nigel I.; Boyd, Derek R.; Sharma, Narain D.; Goodrich, Peter A.; Groocock, Melanie R.; Blacker, A. John; Goode, Paul; Dalton, Howard Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 11 p. 1453 - 1461
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Citation Number: 50
Abstract
... A simple tuning of the reaction conditions allows the isolation of the desired products in good-to-excellent ... to D-threonine [99% enantiomeric excess (ee)] and L-threonine (94% ee) in 26-34% overall yields. ... (5) (a) Murata, K.; Okano, K.; Miyagi, M.; Iwane, H.; Noyori, R.; Ikariya, T ...
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