Design and synthesis of nonpeptide angiotensin II receptor antagonists featuring acyclic imidazole-mimicking structural units
…, L Belvisi, D Poma, A Salimbeni, N Sciammetta…
Index: Angiolini, Mauro; Belvisi, Laura; Poma, Davide; Salimbeni, Aldo; Sciammetta, Nunzio; Scolastico, Carlo Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 11 p. 2013 - 2027
Full Text: HTML
Citation Number: 5
Abstract
Extensive molecular modelling studies, including conformational analysis and the comparison of molecular electrostatic potential distributions, were used to evaluate structural parameters of new antagonists containing acyclic replacements of the N= CN imidazole region. The synthesis and the biological screening of a series of acyl biphenyltetrazole derivatives were planned and realized to gain an insight into the structure–activity ...
Related Articles:
Palladium (II)??Catalyzed Hydration of Alkynylphosphonates to β??Ketophosphonates
[Li, Xiubin; Hu, Gaobo; Luo, Ping; Tang, Guo; Gao, Yuxing; Xu, Pengxiang; Zhao, Yufen Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2427 - 2432]
Synthèse générale et efficace de β-cétophosphonates
[Coutrot, Philippe; Grison, Claude; Lachgar, Mohamed; Ghribi, Abdelaziz Bulletin de la Societe Chimique de France, 1995 , vol. 132, p. 925 - 942]
Novel Cobalt (0)-or Magnesium-Mediated Approaches to β-Ketophosphonates
[Orsini, Fulvia; Di Teodoro, Emanuela; Ferrari, Marinella Synthesis, 2002 , # 12 p. 1683 - 1688]
[Coutrot, Philippe; Ghribi, Abdellaziz Synthesis, 1986 , # 8 p. 661 - 664]
[Coutrot, Philippe; Ghribi, Abdellaziz Synthesis, 1986 , # 8 p. 661 - 664]