Tetrahedron letters

Regiospecific acylations of aromatics and selective reductions of azobenzenes over hydrated zirconia

…, DP Sabde, MK Dongare, A Sudalai, VH Deshpande

Index: Patil; Jnaneshwara; Sabde; Dongare; Sudalai; Deshpande Tetrahedron Letters, 1997 , vol. 38, # 12 p. 2137 - 2140

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Citation Number: 19

Abstract

In a typical reaction, a mixture of 4,4′-dichloroazobenzene (1.25 g; 5 mmol), hydrazine hydrate (0.3 g; 5 mmol), NaHCO 3 (0.84 g; 10 mmol) and hydrated zirconia (125 mg; 10% by wt) in EtOH (20 ml) was refluxed for 10 h. After the reaction was complete (TLC), the catalyst was filtered off, the reaction mixture concentrated and the product purified by flash chromatography to afford the 4,4′-dichlorohydrazobenzene (1.15 g; 90%). Its spectral data: 1 H NMR (200 MHz, ...

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