Stereospecific synthesis of azetidine-cis-2, 3-dicarboxylic acid.

Y Arakawa, T Murakami, Y Arakawa…

Index: Arakawa, Yasushi; Murakami, Tomoaki; Arakawa, Yukimi; Yoshifuji, Shigeyuki Chemical and Pharmaceutical Bulletin, 2003 , vol. 51, # 1 p. 96 - 97

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Citation Number: 10

Abstract

We have previously reported a study of the synthesis of amino acids using Diels–Alder (D–A) adducts of dienes and N-containing dienophiles.1,2) Subsequently, our interests turned to the synthesis of additional amino acids from other N-containing olefins, which can be prepared by pericyclic re- action. In the present paper, we would like to report the synthesis of azetidine-cis-2,3-dicarboxylic acid (1) using the electro- cyclic reaction of 1,2- ...