An iron carbonyl approach to the influenza neuraminidase inhibitor oseltamivir

…, H Gradén, DP Hagberg, T Olsson, N Kann

Index: Bromfield, Karen M.; Graden, Henrik; Hagberg, Daniel P.; Olsson, Thomas; Kann, Nina Chemical Communications, 2007 , # 30 p. 3183 - 3185

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Citation Number: 43

Abstract

Cationic iron carbonyl complexes of cyclohexadienes are versatile building blocks due to the fact that a wide range of nucleophiles can react with the cationic functionality, yielding new carbon–carbon or carbon–heteroatom bonds. 13 In addition, the diene moiety liberated after oxidative decomplexation allows for further transformations. As such, there are many examples of the use of cationic iron carbonyls in the total synthesis of natural products. 14 Our ...