Tetrahedron Letters

Potassium tetracarbonylhydridoferrate: A reagent for the selective reduction of carbonyl groups

JJ Brunet, R Chauvin, F Kindela, D Neibecker

Index: Brunet, Jean-Jacques; Chauvin, Remi; Kindela, Fadjai; Neibecker, Denis Tetrahedron Letters, 1994 , vol. 35, # 47 p. 8801 - 8804

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Citation Number: 9

Abstract

Abstract KHFe (CO) 4 is an efficient reagent for the reduction of electron-deficient ketones (trifluoroacetophenone) and for the selective mono-reduction of the keto group of α- ketocarbonyl compounds such as benzil, methyl benzoylformate, N-methylisatine and methyl pyruvate. The phosphite substituted derivative K [HFe (CO) 3 {P (OMe) 3}] is also an efficient reagent for the reduction of trifluoroacetophenone.