Organometallics

Utility of dysprosium as a reductant in coupling reactions of acyl chlorides: the synthesis of amides and diaryl-substituted acetylenes

W Chen, K Li, Z Hu, L Wang, G Lai, Z Li

Index: Chen, Weifeng; Li, Kebin; Hu, Ziqiang; Wang, Liliang; Lai, Guoqiao; Li, Zhifang Organometallics, 2011 , vol. 30, # 7 p. 2026 - 2030

Full Text: HTML

Citation Number: 9

Abstract

Reduction of acyl chlorides with dysprosium metal has been studied. The reducing ability of dysprosium metal is solvent-dependent. Dysprosium metal, which requires neither any additive nor pretreatment, can promote the cross-coupling of acyl chlorides in DMF or DEF to give amides in good yields. When the reaction was performed in N, N-dimethylacetamide, the reductive self-coupling reaction of aroyl chloride took place smoothly and afforded the ...