Effect of ring A and ring B substitution on the cytotoxic potential of pyrazole tethered chalcones
K Nepali, K Kadian, R Ojha, R Dhiman, A Garg…
Index: Nepali, Kunal; Kadian, Kanika; Ojha, Ritu; Dhiman, Rajni; Garg, Atul; Singh, Gagandip; Buddhiraja, Abhishek; Bedi, Preet Mohinder Singh; Dhar, Kanaya Lal Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 2990 - 2997
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Citation Number: 19
Abstract
Abstract Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are collectively known as chalcones. The cytotoxic potential of chalcones which consists of C 6–C 3–C 6 units gets enhanced by the incorporation of pyrazole ring as proved by our earlier studies. Thus in the present work, pyrazoles of chalcones with ring A substituted by furan, naphthalene and variety of substituted phenyl ...
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