One??Pot Sequential Synthesis of Ethers from an Aliphatic Carboxylic Acid and an Alcohol by Indium??Catalyzed Deoxygenation of an Ester

…, T Moriya, R Ikeda, T Konakahara

Index: Sakai, Norio; Usui, Yuta; Moriya, Toshimitsu; Ikeda, Reiko; Konakahara, Takeo European Journal of Organic Chemistry, 2012 , # 24 p. 4603 - 4608

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Citation Number: 9

Abstract

Abstract We have developed a widely applicable and direct method of etherification from a carboxylic acid and an alcohol by indium-catalyzed deoxygenation of the transient ester formed in a one-pot reaction. This simple catalytic reducing system appears to be remarkably tolerant of several functional groups including alkenes, halogens, nitro and heterocyclic groups.

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