Tetrahedron

An efficient synthetic route to functionalized δ-lactams

A Samarat, JB Kraïem, TB Ayed, H Amri

Index: Samarat, Ali; Ben Kraiem, Jihene; Ben Ayed, Taicir; Amri, Hassen Tetrahedron, 2008 , vol. 64, # 40 p. 9540 - 9543

Full Text: HTML

Citation Number: 6

Abstract

Six-membered nitrogen-containing heterocycles are common skeletons in many natural products and exhibit diverse and important biological properties. 1 and 2 Alkaloids that contain the piperidine ring are targets for medicinal chemistry. 3, 4, 5, 6 and 7 Accordingly, functionalized δ-lactams have been generally used as precursors of the corresponding piperidines. 8, 9 and 10 Functionalized δ-lactams and structurally related compounds have attracted considerable attention ...

Related Articles:

Construction of Hydroxylated Alkaloids (.+-.)-Mannonolactam,(.+-.)-Deoxymannojirimycin, and (.+-.)-Prosopinine through Aza-Annulation

[Cook, Gregory R.; Beholz, Lars G.; Stille, John R. Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3575 - 3584]

A short synthesis of (±)-cytisine

[Organic and Biomolecular Chemistry, , vol. 2, # 13 p. 1825 - 1826]

Construction of Hydroxylated Alkaloids (.+-.)-Mannonolactam,(.+-.)-Deoxymannojirimycin, and (.+-.)-Prosopinine through Aza-Annulation

[Journal of Organic Chemistry, , vol. 59, # 13 p. 3575 - 3584]

More Articles...