Journal of the American Chemical Society

Synthesis of Cyclohexestrol

GP Mueller, R May

Index: Mueller; May Journal of the American Chemical Society, 1949 , vol. 71, p. 3313,3316

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Citation Number: 11

Abstract

Much of the search for new synthetic estrogens has consisted either of substituting groups within the essentially intact hexestrol skeleton, or of building other structures also supposedly capable of simulating the nuclear form of the estrogenic hormone. The synthesis of the cyclohexane analog, for which previous attempts have been rep~ rted,~ has been completed. phenylcyclohexanone, O and conversely for a 1: 1 ratio.