Preparation of bicyclic lactones: precursors for the synthesis of paniculides B and C

…, CL Gibson, CJ Swain, DJ Tapolczay

Index: Baker, Raymond; Gibson, Colin L.; Swain, Christopher J.; Tapolczay, David J. Journal of the Chemical Society, Chemical Communications, 1984 , # 9 p. 619 - 621

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Abstract

A stereoselective approach to the paniculide skeleton is reported utilizing an approach based on the dilithioacetate opening of an epoxide and demonstrating the high degree of regio-and stereo-control possible in this reaction, epoxidation, reduction and phenylselenation reactions.