Amino acids

Synthesis of camptothecin–amino acid carbamate linkers

MA Etienne, M Kostochka, JA Fuselier, DH Coy

Index: Etienne, Marcus A.; Kostochka, Mikhail; Fuselier, Joseph A.; Coy, David H. Amino Acids, 2012 , vol. 42, # 5 p. 1727 - 1733

Full Text: HTML

Citation Number: 2

Abstract

Abstract A more convenient and facile approach for the synthesis and production of camptothecin–amino acids carbamate linkers, that can be used in the synthesis of bioconjugate peptides JF-10-81, JF-10-71, and other peptide analogs designed to target somatostatin receptors has been described.

Related Articles:

Building units for N-backbone cyclic peptides. 3. Synthesis of protected N α-(ω-aminoalkyl) amino acids and N α-(ω-carboxyalkyl) amino acids

[Muller, Dan; Zeltser, Irena; Bitan, Gal; Gilon, Chaim Journal of Organic Chemistry, 1997 , vol. 62, # 2 p. 411 - 416]

Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors

[Millet, Regis; Urig, Sabine; Jacob, Judit; Amtmann, Eberhard; Moulinoux, Jacques-Philippe; Gromer, Stephan; Becker, Katja; Davioud-Charvet, Elisabeth Journal of Medicinal Chemistry, 2005 , vol. 48, # 22 p. 7024 - 7039]

Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors

[Millet, Regis; Urig, Sabine; Jacob, Judit; Amtmann, Eberhard; Moulinoux, Jacques-Philippe; Gromer, Stephan; Becker, Katja; Davioud-Charvet, Elisabeth Journal of Medicinal Chemistry, 2005 , vol. 48, # 22 p. 7024 - 7039]

Novel versatile fullerene synthons

[Kordatos; Da Ros; Bosi; Vazquez; Bergamin; Cusan; Pellarini; Tomberli; Baiti; Pantarotto; Georgakilas; Spalluto; Prato Journal of Organic Chemistry, 2001 , vol. 66, # 14 p. 4915 - 4920]

Conjugates of PNA with naphthalene diimide derivatives having a broad range of DNA affinities

[Seitz, Oliver; Koehler, Olaf Chemistry - A European Journal, 2001 , vol. 7, # 18 p. 3911 - 3925]

More Articles...