Structure-Activity Relationship of. alpha.-Galactosylceramides against B16-Bearing Mice

…, Y Koezuka, E Kobayashi, H Fukushima

Index: Morita; Motoki; Akimoto; Natori; Sakai; Sawa; Yamaji; Koezuka; Kobayashi; Fukushima Journal of Medicinal Chemistry, 1995 , vol. 38, # 12 p. 2176 - 2187

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Citation Number: 506

Abstract

Monoglycosylated ceramides such as galactosylceramide (GalCer) are important surface molecules found in virtually all cells, and glycosphingolipids related to GalCer and their metabolites play important roles in promoting the regulation of nerve cells, l regulating protein kinase C activities, 2 and modulating the function of the hormone re~ eptor.~ Recently, GalCer was identified as essential components of the neural receptor for type 1 ...