Medicinal Chemistry Research

Synthesis and evaluation of antibacterial and antitubercular activities of some novel imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives

SD Joshi, K Manish, A Badiger

Index: Joshi; Manish; Badiger, Aravind Medicinal Chemistry Research, 2013 , vol. 22, # 2 p. 869 - 878

Full Text: HTML

Citation Number: 10

Abstract

Abstract A series of 2, 5, 6-trisubstituted imidazo [2, 1-b][1, 3, 4] thiadiazoles were synthesized, structures of the compounds were elucidated and evaluated for antitubercular activity against Mycobacterium tuberculosis H37Rv using microplate alamar blue assay (MABA) method, antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Vibrio cholera, and Escherichia coli by broth micro dilution assay method. Some compounds ...