Tetrahedron letters

Reductive electrophilic substitution of pyrogallol derivatives: Synthesis of 2, 3-disubstituted phenols

U Azzena, G Melloni, L Pisano

Index: Azzena, Ugo; Melloni, Giovanni; Pisano, Luisa Tetrahedron Letters, 1993 , vol. 34, # 35 p. 5635 - 5638

Full Text: HTML

Citation Number: 19

Abstract

Abstract 1-2-Dimethoxy-3-methoxymethoxybenzene, 1, was used as the starting material for the transformation of a 1, 2, 3-trioxybenzene into various 1-oxy-2, 3-dicarbobenzenes, via regioselective reductive electrophilic substitution of the 2-methoxy group followed by Pd- catalyzed cross-coupling reaction.

Related Articles:

The synthesis and selected chemistry of 6-alkyl-6-carbalkoxy-and 6-alkyl-6-(aminocarbonyl)-2, 4-cyclohexadien-1-ones and cyclohexadienone ketals

[Schultz, Arthur G.; Dittami, James P.; Lavieri, Frank P.; Salowey, Christina; Sundararaman, Padmanabhan; Szymula, Mary Beth Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4429 - 4440]

On the role of copper and iron in DNA cleavage by ochratoxin A. Structure-activity relationships in metal binding and copper-mediated DNA cleavage

[Ardus, Jason A.; Gillman, Ivan G.; Manderville, Richard A. Canadian Journal of Chemistry, 1998 , vol. 76, # 6 p. 907 - 918]

More Articles...