Chemical Communications

2, 2-Dimethyl cyclopentanones by acid catalyzed ring expansion of isopropenylcyclobutanols. A short synthesis of (±)-α-cuparenone and (±)-herbertene

AM Bernard, A Frongia, F Secci, PP Piras

Index: Bernard, Angela M.; Frongia, Angelo; Secci, Francesco; Piras, Pier P. Chemical Communications, 2005 , # 30 p. 3853 - 3855

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Citation Number: 19

Abstract

2, 2-Dimethyl cyclopentanones are readily prepared by acid catalyzed ring expansion of isopropenylcyclobutanols; the method allows ready access to the family of sesquiterpenes cuparanes and herbertanes, as demonstrated by the synthesis of (±)-α-cuparenone and the direct precursor of (±)-herbertene.