4-Aminopyridine derivatives with anticholinesterase and antiamnesic activity

L Scipione, D De Vita, A Musella, L Flammini…

Index: Scipione, Luigi; De Vita, Daniela; Musella, Alessandra; Flammini, Lisa; Bertoni, Simona; Barocelli, Elisabetta Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 1 p. 309 - 312

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Citation Number: 9

Abstract

Several carbamate derivatives of 4-aminopyridine were synthesized and their anticholinesterase activity was evaluated. Compound 4d showed the highest inhibitory effect blocking non-competitively acetylcholinesterase and competitively butyrylcholinesterase. ...