2-Amino-1, 1, 3-tricyanopropene in heterocyclic synthesis: Novel synthesis of thiopyran pyridinethiones and nicotinonitrile derivatives

AMS Eldin

Index: Salah Eldin, Abdellatif M. Phosphorus, Sulfur and Silicon and the Related Elements, 2003 , vol. 178, # 10 p. 2215 - 2223

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Citation Number: 2

Abstract

2-Amino-1, 1, 3-tricyano-3-bromopropene was obtained from bromination of malononitrile dimer, 2-amino-1, 1, 3-tricyanopropene with N-bromo-succinimide (NBS). The reactions of this bromo derivative with sodium hydrogen sulfide and thioglycollic acid afforded thiophene and thiopyran derivatives respectively. A novel synthesis of pyridinethione and nicotinonitrile derivatives by using 3-amino-4, 4-dicyano-3-butenethioamide as starting material are ...