Organic letters

Radical cyclization approach to spirocyclohexadienones

F González-López de Turiso, DP Curran

Index: Gonzalez-Lopez De Turiso, Felix; Curran, Dennis P. Organic Letters, 2005 , vol. 7, # 1 p. 151 - 154

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Citation Number: 84

Abstract

Cyclization of an aryl radical at the ipso position of ap-O-aryl-substituted acetamide or benzamide generates oxindoles or quinolones bearing spirocyclohexadienone rings. This versatile reaction is applied to formal syntheses of the vasopressin inhibitor SR121463A and aza-galanthamine.