Journal of heterocyclic chemistry

Sulfur derivatives of 1??methylpyrrole

S Gronowitz, R Kada

Index: Gronowitz, Salo; Kada, Rudolf Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 1041 - 1043

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Citation Number: 9

Abstract

Abstract Metalation of 1-methylpyrrole using n-butyllithium and tetramethylethylenediamine (TMEDA) in ether furnished 1-methyl-2-pyrrolyllithium, which in turn was converted to 1- methyl-2-methylthiopyrrole upon treatment with dimethyldisulfide. Further formylation with dimethylformamide, phosphorus oxychloride in dichloroethane led to the corresponding pyrrole-2-carboxaldehyde, which was then condensed with malononitrile and ...

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