The Journal of Organic Chemistry

1-Bromobenzocyclobutene: a convenient entry into the benzocyclobutene ring system

MR DeCamp, LA Viscogliosi

Index: DeCamp, Mark R.; Viscogliosi, Lori A. Journal of Organic Chemistry, 1981 , vol. 46, # 19 p. 3918 - 3920

Full Text: HTML

Citation Number: 7

Abstract

The thermally induced benzocyclobutene-o-quinodi-methane interconversion has been exploited recently for the construction of complex polycyclic compounds. 2 The synthetic design involves interception of a nascent o-quinodimethane by a remote multiple bond in an intramolecular Diels-Alder reaction. The requisite starting material for such a process is a benzocyclobutene appropriately elaborated at the 1-position. Conventional approaches to ...