ARKIVOC

A simple synthesis of 4-aroyl-5-methyl-1H-imidazol-2 (3H)-one derivatives (Enoxymone analogues) from aryl methyl ketones via enaminones

J Bezenšek, U Grošelj, K Stare, J Svete, B Stanovnik

Index: Bezensek, Jure; Groselj, Uros; Stare, Katarina; Svete, Jurij; Stanovnik, Branko Arkivoc, 2014 , vol. 2014, # 2 p. 294 - 307

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Citation Number: 1

Abstract

Abstract Aryl methyl ketones 1a-e gave with N, N-dimethylacetamide dimethylacetal (DMADMA)(E)-1-aryl-3-(dimethylamino)-but-2-en-1-ones 2a-e. Substitution of the N, N- (dimethylamino) group in the reaction with ammonium acetate afforded the corresponding (Z)-3-amino-1-aryl-but-2-en-1-ones 3a-e. In the reaction of 3a-e with diethyl azodicarboxylate intermediates 4a-e were formed, which were, in most cases without ...