Bulletin of the Chemical Society of Japan

The acid catalyzed decomposition of diazo compounds. I. Synthesis of oxazoles in the BF3 catalyzed reaction of diazo carbonyl compounds with nitriles.

T Ibata, R Sato

Index: Ibata,T.; Sato,R. Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 3597 - 3600

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Citation Number: 31

Abstract

The BF 3-catalyzed decomposition of diazo carbonyl compounds in nitriles have afforded the corresponding oxazoles in high yields. This method is applicable to diazo carbonyl compounds such as m-and p-substituted diazoacetophenones, ethyl diazoacetate, 1, 2- diphenyl-2-diazoethanone, dibenzoyldiazomethane, and dimethyl diazomalonate. Bis (diazo ketone) s such as terminal bis (diazoacetylated) alkanes (III 1− 4: n= 6, 8, 10, 12) ...