IspC as target for antiinfective drug discovery: synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters

…, T Gräwert, CT Behrendt, P Werner…

Index: Casadei, Maria Antonietta; Rienzo, Barbara Di; Inesi, Achille; Moracci, Franco Micheletti Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 3 p. 375 - 378

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Abstract

... Journal of Medicinal ... 2013, 56 (20), pp 8151–8162. DOI: 10.1021/jm4012559. Publication Date (Web): September 13, 2013. Copyright © 2013 American Chemical Society. ... Table 1. IC 50 Values of Thia Analogs 5 and 7 versus IspC of Escherichia coli, Mycobacterium tuberculosis ...

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