Stereoselective synthesis of the cytotoxic 14-membered macrolide aspergillide A

…, CA Angulo-Pachón, J Murga, M Carda…

Index: Troast, Dawn M.; Yuan, Jiayi; Porco Jr., John A. Advanced Synthesis and Catalysis, 2008 , vol. 350, # 11-12 p. 1701 - 1711

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Citation Number: 23

Abstract

... Attempts at macrolactonization under Shiina,(19) Trost,(20) or Keck(21) conditions were also fruitless. ... In summary, the synthesis of the cytotoxic, 14-membered macrolide aspergillide A in a stereoselective ... br, OH), 1724 (C═O) cm −1 ; HR ESMS m/z 277.1417 (M + Na + ), calcd ...