Journal of medicinal chemistry

Compounds Acting on the Central Nervous System. IV. 4-Substituted 2, 3-Polymethylenequinolines

GK Patnaik, MM Vohra

Index: Patnaik,G.K. et al. Journal of Medicinal Chemistry, 1966 , vol. 9, p. 483 - 488

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Citation Number: 16

Abstract

h number of 4-X-siibstitiited amino-and carbamoyl-2, 3-polymethyleiiequi1ioliiies have been synthesized and have been foiuid to exhibit a wide spectrum of pharmacological properties, which incalade analgetic, local anesthetic, analeptic, and respiratory stimulant activities. In particular 4-(4-morpholin~-1)-2, 3-pentamethylenequinoline has shown significant and promising analeptic and respiratory stimulant activity.