Synthesis of spirocyclic 4, 5, 5a, 6, 7, 8-hexahydro-1H-pyrazolo [3, 4-e] indolizine derivatives

…, EV D'yachenko, TV Glukhareva, YY Morzherin

Index: Eltsov, Oleg S.; D'Yachenko, Elisaveta V.; Glukhareva, Tatiana V.; Morzherin, Yury Yu. Mendeleev Communications, 2005 , # 3 p. 119 - 120

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Citation Number: 6

Abstract

The condensation of 3-methyl-1-phenyl-5-pyrrolidinopyrazole-4-carboxaldehyde with N, N- dimethylbarbituric acid or Meldrum's acid followed by cyclization of the Knövenagel product by in a 'tert-amino effect'reaction resulted in the heterocyclic spiroderivatives of pyrazolo [3, 4- e] indolizine.