RhI-catalyzed aldol-type reaction of organonitriles under mild conditions
A Goto, K Endo, Y Ukai, S Irle, S Saito
Index: Goto, Akihiro; Endo, Kohei; Ukai, Yu; Irle, Stephan; Saito, Susumu Chemical Communications, 2008 , # 19 p. 2212 - 2214
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Citation Number: 14
Abstract
The nitrile functionality is synthetically versatile for many functional group conversions. 1 Incorporation of a nitrile fragment into a carbon framework provides rapid access to a number of useful chemicals such as α-amino and α-hydroxy carboxylic acid derivatives as well as nitrile-branching polymers. Concerned with this goal, cyanation strategies 2 have been most widely employed so far. In contrast, aldol-type reactions of alkylnitriles are those in which nitriles serve as ...
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