Spin Trapping with 5-Methyl-5-phenylpyrroline N-Oxide. A Replacement for 5, 5-Dimethylpyrroline N-Oxide

N Sankuratri, EG Janzen, MS West…

Index: Sankuratri, Nagaraju; Janzen, Edward G.; West, Melinda S.; Poyer, J. Lee Journal of Organic Chemistry, 1997 , vol. 62, # 4 p. 1176 - 1178

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Citation Number: 13

Abstract

5, 5-Dimethylpyrroline N-oxide (DMPO) 1 has become the most commonly used spin trap in biological systems to date. This is because the hydroxyl radical spin adduct gives a simple and distinctive EPR spectrum2 consisting of four peaks with relative intensity 1: 2: 2: 1, and the superoxide/hydroperoxyl radical spin adduct gives a different but also distinctive multiline EPR spectrum2 composed of 6 major peaks plus additional partially resolved ...