[2+ 2+ 2]??Cycloaddition of 4??Hydroxy??Substituted Enediynes to 2??Hydroxy??Substituted Decahydrophenanthrenes

U Groth, N Richter, A Kalogerakis

Index: Groth, Ulrich; Richter, Norbert; Kalogerakis, Aris European Journal of Organic Chemistry, 2003 , # 23 p. 4634 - 4639

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Citation Number: 10

Abstract

Abstract Enediynes rac-4 were prepared in seven steps with an overall yield of 31% starting from 4-pentyn-1-ol (5). A cobalt mediated [2+ 2+ 2]-cycloaddition of these enediynes and subsequent removal of the metal fragment afforded the decahydrophenanthrenes rac-3/13 in 37− 56% yield.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)