Benzylation of sugar polyols by means of the PTC method

W Szeja, I Fokt, G Grynkiewicz

Index: Szeja, W.; Fokt, I.; Grynkiewicz, G. Recueil des Travaux Chimiques des Pays-Bas, 1989 , vol. 108, # 6 p. 224 - 226

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Citation Number: 25

Abstract

Abstract Studies on benzylation of hydrophilic carbohydrate derivatives with benzyl chloride, using a phase-transfer technique, have led to the conclusion that alkylation of a substrate can be greatly facilitated by the introduction of a “co-catalyst”(eg a tertiary alcohol) and/or a co-solvent (eg DMSO) to the reaction mixture. Efficient procedures for benzylation of sugar derivatives having three to eight hydroxyl groups per molecule, in a two-phase system ...