Tetrahedron letters

Phosphazene bases for the preparation of biaryl thioethers from aryl iodides and arenethiols

C Palomo, M Oiarbide, R López, E Gómez-Bengoa

Index: Palomo, Claudio; Oiarbide, Mikel; Lopez, Rosa; Gomez-Bengoa, Enrique Tetrahedron Letters, 2000 , vol. 41, # 8 p. 1283 - 1286

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Citation Number: 161

Abstract

In the presence of phosphazene P2-Et base as well as 1, 8-diazabicyclo [5.4. 0] undec-7- ene (DBU) the coupling of aryl iodides with arenethiols only requires catalytic amounts of CuBr. Under these conditions the reaction can be performed in refluxing toluene to give biaryl thioethers in excellent yields.

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