Journal of heterocyclic chemistry
The synthesis of ring??expanded analogues of xanthine containing the imidazo [4, 5??e][1, 4] diazepine ring system
RS Hosmane, A Bhan
Index: Hosmane, Ramachandra S.; Bhan, Anila Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 2189 - 2196
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Citation Number: 21
Abstract
Abstract The synthesis of 4, 5, 7, 8-tetrahydro-6H-imidazo [4, 5-e][1, 4] diazepine-5, 8-dione and its several 1-and 3-alkyl (aralkyl) derivatives 2 has been reported. Mechanistic explorations of the final synthetic step as well as structural confirmation of a final product 2d by single-crystal X-ray diffraction analyses have also been presented.
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