Tetrahedron Letters

Facile synthesis of 2-bromoindoles by ligand-free CuI-catalyzed intramolecular cross-coupling of gem-dibromoolefins

B Jiang, K Tao, W Shen, J Zhang

Index: Jiang, Baishan; Tao, Kemei; Shen, Wang; Zhang, Jiancun Tetrahedron Letters, 2010 , vol. 51, # 48 p. 6342 - 6344

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Citation Number: 14

Abstract

A mild and efficient synthesis of 2-bromoindoles by ligand-free CuI-catalyzed intramolecular cross-coupling of gem-dibromoolefins was developed. Reactions were carried out in toluene at room temperature and the corresponding 2-bromoindoles were obtained in excellent yields.