Tetrahedron

Synthesis of furans by cyclization of 2-En-4-yn-1-ols in the presence of ruthenium and palladium catalysts

B Seiller, C Bruneau, PH Dixneuf

Index: Seiller, Benedicte; Bruneau, Christian; Dixneuf, Pierre H. Tetrahedron, 1995 , vol. 51, # 47 p. 13089 - 13102

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Citation Number: 89

Abstract

Substituted furans have been synthesized in the presence of ruthenium catalysts under neutral and mild conditions via cyclization of primary and secondary enynols of type (Z)- HCC-C (Me)= CH-CH (R) OH containing a terminal triple bond. The intramolecular addition of the hydroxy group to the triple bond of internal (Z)-enynols is also possible upon palladium catalysis.