Australian Journal of Chemistry

Cross-linking of amino acids by formaldehyde. 13C NMR spectra of model compounds

MK Dewar, RB Johns, DP Kelly, JF Yates

Index: Dewar,M.K. et al. Australian Journal of Chemistry, 1975 , vol. 28, p. 917 - 924

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Citation Number: 17

Abstract

Abstract The use of 13 C NMR for the identification of the site of cross-linking of amino acids by formaldehyde has been evaluated by use of model compounds, such as 2, 4- dimethylphenol for tyrosine. The 13 C chemical shifts of the formaldehyde-derived methylene carbons occur within the range 50-60 ppm downfield from Me 4 Si. Estimated shifts in lysine-lysine and tyrosine-glutamine cross-linked systems fall just outside this ...