l-Proline derived mimics of the non-haem iron active site catalyse allylic oxidation in acetonitrile solutions

VJ Dungan, BML Poon, ES Barrett, PJ Rutledge

Index: Dungan, Victoria J.; Poon, Belinda M.-L.; Barrett, Elizabeth S.; Rutledge, Peter J. Tetrahedron Letters, 2013 , vol. 54, # 10 p. 1236 - 1238

Full Text: HTML

Citation Number: 7

Abstract

Non-haem iron complexes are important reagents for the oxidative functionalisation of C–H bonds. Peptidomimetic ligands derived from l-proline, pyridine-2, 6-dimethanol and pyridine- 2, 6-dicarboxylic acid have been combined with iron (II) triflate and hydrogen peroxide in acetonitrile. The resulting complexes convert cyclohexene into the allylic oxidation products, 2-cyclohexen-1-ol, 2-cyclohexen-1-one and 2-cyclohexenyl hydroperoxide in high ...