Synthetic Communications

Regioselective α-Bromination of Aralkyl ketones using N-bromosuccinimide in the presence of montmorillonite K-10 clay: A simple and efficient method

RB Mohan, NCG Reddy

Index: Mohan, Reddy Bodireddy; Reddy, N. C. Gangi Synthetic Communications, 2013 , vol. 43, # 19 p. 2603 - 2614

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Citation Number: 13

Abstract

A simple and more convenient method has been developed for regioselective α-bromination of various aralkyl ketones with N-bromosuccinimide (NBS) in the presence of Montmorillonite K-10 catalyst in methanol at 60–65 °C. The present procedure offers advantages of short reaction time, simple workup, good yields of products and reusability of the catalyst for four times without loss of activity. ... Supplemental materials are available for this article. Go to the ...

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