Tetrahedron

The “two-fold reaction” benchmark applied to the copper catalyzed assembling of 1ω-difunctional hydrocarbon chains

M Schlosser, H Bossert

Index: Schlosser, Manfred; Bossert, Henri Tetrahedron, 1991 , vol. 47, # 32 p. 6287 - 6292

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Citation Number: 32

Abstract

Long-chain hydrocarbons carrying vinyl groups, chlorine atoms or oxygen functions at the terminal positions can be prepared with excellent yields by copper mediated coupling of alkyl tosylates and Grignard reagents. No “breeding stage” is necessary if the cuprous complex dilithium trichlorocuprate rather than a cupric salt is employed as the catalyst.