Tetrahedron

Reductive lithiation of alkoxy-substituted benzyl methyl ethers and connection with cross-coupling reactions

U Azzena, G Dettori, R Pireddu, L Pisano

Index: Azzena, Ugo; Dettori, Giovanna; Pireddu, Roberta; Pisano, Luisa Tetrahedron, 2004 , vol. 60, # 7 p. 1617 - 1623

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Citation Number: 8

Abstract

2-and 4-Ethoxymethoxybenzyl methyl ethers were employied as useful starting materials for the synthesis of 1, 2-or 1, 4-dicarbo-substituted benzenes. The proposed reaction sequence involves connection between the reductive lithiation of benzyl alkyl ethers and the metal- catalyzed cross-coupling reaction of aromatic triflates.