Chromium (VI) oxide catalyzed oxidation of sulfides to sulfones with periodic acid
L Xu, J Cheng, ML Trudell
Index: Xu, Liang; Cheng, Jie; Trudell, Mark L. Journal of Organic Chemistry, 2003 , vol. 68, # 13 p. 5388 - 5391
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Citation Number: 107
Abstract
A highly efficient and selective oxidation of sulfides to sulfones with periodic acid catalyzed by CrO3 is described. A variety of electron-rich and electron-deficient sulfides were oxidized to sulfones with 2 mol% CrO3 in acetonitrile at room temperature in excellent yields. Sulfides with other readily oxidized functional groups were selectively oxidized to sulfones in high yields with 10 mol% CrO3 in ethyl acetate/acetonitrile at-35° C.
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