Synthesis of optically active calanolides A and B
PP Deshpande, F Tagliaferri, SF Victory…
Index: Deshpande, Prashant P.; Tagliaferri, Frank; Victory, Samuel F.; Yan, Shija; Baker, David C. Journal of Organic Chemistry, 1995 , vol. 60, # 10 p. 2964 - 2965
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Citation Number: 53
Abstract
Recently calophyllum coumarins such as the calanolides'(1 and 2) and the inophyllum~~,~(3 and 4) have attracted considerable attention as potent inhibitors of human immune deficiency virus-1 (HN-1) reverse transcriptase (RT). Because these compounds show a mechcalanolide A (1): R,= n-propyl, R,= OH, R,= H calanolide B (2): R,= n-propyl, R,= H, R,= OH inophyllum B (3): R,= phenyl, R,= OH, R,= H inophyllum P (4): R,= phenyl, ...
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