The Baylis-Hillman reaction: One-pot facile synthesis of 2, 4-functionalized 1, 4-pentadienes

…, DS Sharada, N Kumaragurubaran…

Index: Basavaiah, Deevi; Sharada, Duddu S.; Kumaragurubaran, Nagaswamy; Reddy, Ravi Mallikarjuna Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 7135 - 7137

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Citation Number: 66

Abstract

The Baylis−Hillman reaction is a three-component reaction involving the construction of the carbon−carbon bond between the α-position of activated alkene and a carbon electrophile under the influence of a catalyst (most commonly tertiary amines, particularly, DABCO), leading to the formation of interesting densely functionalized molecules whose applications in a variety of synthetic transformation methodologies have been well documented in the literature. 1-3 In ...