A synthetic receptor for dinucleotides

A Galan, J De Mendoza, C Toiron, M Bruix…

Index: Galan, Amalia; De Mendoza, Javier; Toiron, Catherine; Bruix, Marta; Deslongchamps, Ghislain; Rebek Jr., Julius Journal of the American Chemical Society, 1991 , vol. 113, # 24 p. 9424 - 9425

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Citation Number: 63

Abstract

Complexation of biorelevant targets with synthetic receptors continues to provide information regarding recognition at the molecular leveL2 One tactic involves the concatenation of modular subunits with complementarity to specific domains of the target. Here we apply this means to develop a system (receptor 1) for the complexation of 2'-deoxyadenylyl (3'+ 5')-2'- deoxyadenosine (d (AA)) and give evidence of its success.