Synthesis, NMR spectral studies and antimicrobial evaluation of some 2-(benzothiazol-2-yl)-1-(alkyl-2r, 6c-diarylpiperidin-4-ylidine) hydrazine derivatives

JJF Xavier, R Venkateswaramoorthi, A Kamaraj…

Index: Xavier, J. John Francis; Venkateswaramoorthi; Kamaraj; Krishnasamy Medicinal Chemistry Research, 2013 , vol. 22, # 11 p. 5105 - 5111

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Abstract

Abstract Substituted 2-(benzothiazol-2-yl)-1-(alkyl-2, 6-diarylpiperidin-4-ylidine) hydrazines 10–17 were synthesized by the condensation of different 2 r, 6 c-diarylpiperidin-4-ones 1–8 with 2-hydrazinobenzothiazole 9. All the synthesized compounds were investigated in solution and in the solid state by IR, 1 H, 13 C and 2D NMR spectral techniques. The structure–activity relationships were studied by the screening of the antimicrobial activity ...