Expeditious access to unprotected racemic pyroglutamic acids

J Isaacson, CB Gilley, Y Kobayashi

Index: Mkhairi, A; Hamelin, J. Tetrahedron Letters, 1986 , vol. 27, # 37 p. 4435 - 4436

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Citation Number: 30

Abstract

... Volume: Page ... J. Org ... Levulinic acid (2) is known to participate in the U4C-3CR to give an anilide of type 3, so this γ-ketoacid was used in our initial screen of amines (Table 1). Although p-methoxybenzylamine gives the Ugi product in good yield, 8 we preferred to ...