Synthesis and biological evaluation of functionalized coumarins as acetylcholinesterase inhibitors

Q Shen, Q Peng, J Shao, X Liu, Z Huang, X Pu…

Index: European Journal of Medicinal Chemistry, , vol. 40, # 12 p. 1307 - 1315

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Citation Number: 69

Abstract

... European Journal of Medicinal Chemistry. ... Yield 80%, mp 190–192 °C; IR(KBr) v ˜ : 3159, 1679, 1652, 1600, 1451 cm –1 ; FAB-MS m/z:177([M + H] + ), 154([M–OH] + ); 1 H NMR(CDCl 3 )δ: 9.31 (s, 1H, 7-OH), 7.61 (d, 1H, J = 8.5, 1.0 Hz, 5-H), 6.85 (m, 1H, 6-H), 6.74 (d, 1H, J ...