Novel 1, 4-dihydropyridine calcium antagonists. I. Synthesis and hypotensive activity of 4-(substituted pyridyl)-1, 4-dihydropyridine derivatives.

足森厚之, 小野泰蔵, 内田武, 大滝裕, 深谷力…

Index: Chemical and Pharmaceutical Bulletin, , vol. 38, # 9 p. 2446 - 2458

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Citation Number: 75

Abstract

... Chemistry Synthesis of 1,4-Dihydropyridine Derivatives from Sub- stituted Pyridinecarboxaldehydes (5) Prepared compounds are listed in Tables l ... l 0 Me Me CH2CH2NMe2 diltiazem N02 /Me CDZCH2CH2N~\ CH2 Me H nicardipine 1990 Pharmaceutical Society of ... 2450 ...

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